Phosphoinositides in FCgamma receptor signaling.
نویسنده
چکیده
Fcgamma receptors mediate a variety of immune responses to IgG-containing complexes. Virtually all of these responses appear to be regulated by phosphoinositides, in particular phosphatidylinositol (4,5)P2 and phosphatidylinositol (3,4,5)P3. Possible downstream effectors of phosphoinositides involved in multiple FcgammaR-mediated events are discussed, as are elements of the signaling pathways that may couple Fcgamma receptors to the enzymes of phosphoinositide metabolism.
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عنوان ژورنال:
- Frontiers in bioscience : a journal and virtual library
دوره 11 شماره
صفحات -
تاریخ انتشار 2006